EX-23.1 4 drrx-ex231_10.htm EX-23.1

Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in the following Registration Statements:

| (1) | Registration Statements (Form S-8 Nos. 333-126990 and 333-98939) pertaining to the DURECT Corporation 2000 Directors’ Stock Option Plan,

| (2) | Registration Statements (Form S-8 Nos. 333-166700, 333-161025, 333-152968, 333-124701, 333-86110) pertaining to the DURECT Corporation 2000 Employee Stock Purchase Plan and the DURECT Corporation 2000 Stock Plan,

| (3) | Registration Statements (Form S-8 Nos. 333-212842,333-197980, 333-176113, 333-120405, 333-108390 and 333-226524) pertaining to the DURECT Corporation 2000 Stock Plan,

| (4) | Registration Statements (Form S-8 No. 333-240326, 333-219832, 333-206084 and 333-170349) pertaining to the DURECT Corporation 2000 Employee Stock Purchase Plan,

| (5) | Registration Statement (Form S-8 No. 333-47400) pertaining to the DURECT Corporation 2000 Employee Stock Purchase Plan and the DURECT Corporation 2000 Stock Plan,

| (6) | Registration Statement (Form S-8 No. 333-61224) pertaining to the DURECT Corporation 2000 Employee Stock Purchase Plan, the DURECT Corporation 2000 Stock Plan, and

| (7) | Registration Statements (Form S-3 Nos. 333-108398, 333-108396 and 333-226518) of DURECT Corporation,

of our report dated March 5, 2021, with respect to the financial statements and schedule of DURECT Corporation included in this Annual Report (Form 10-K) of DURECT Corporation for the year ended December 31, 2020.

/s/ ERNST & YOUNG LLP

Redwood City, California

March 5, 2021