EX-8.1 5 exh_81.htm EXHIBIT 8.1

EXHIBIT 8.1

LIST OF SUBSIDIARIES |
Name |  | Jurisdiction |  | Percentage of ownership |
iOx Therapeutics Limited1 |  | United Kingdom |  | 100% |
SalvaRx Limited |  | British Virgin Islands |  | 100% |
Tarus Therapeutics Limited1, 2 |  | British Virgin Islands |  | 100% |
Saugatuck Therapeutics Limited3 |  | British Virgin Islands |  | 70% |
Portage Development Services, Inc. |  | U.S.A. |  | 100% |
SalvaRx LLC1 |  | U.S.A. |  | 100% |
Saugatuck Rx LLC4 |  | U.S.A. |  | 100% |
Tarus Therapeutics LLC |  | U.S.A. |  | 100% |
Stimunity S. A.5 |  | France |  | 48.9% |
1 Wholly-owned subsidiary of SalvaRx Limited |  |  |  |  |
2 Formerly Intensity Holdings Limited |  |  |  |  |
3 A subsidiary of SalvaRx Limited |  |  |  |  |
4 Wholly-owned subsidiary of Saugatuck Therapeutics Limited |  |  |  |  |
5 Ownership held through iOx Therapeutics Limited |  |  |  |  |